Dynamic Languages on the the Desktop

Ted's looking for examples of popular (for some definition of popular)
desktop applications written in dynamic languages...

http://www.sauria.com/blog/2008/10/10/retry-dynamic-languages-for-desktop-apps/

Certainly emacs.

I've used several Smalltalk desktop applications over the years. The
one perhaps most in the mainstream would be James Robertson's Bottom
Feeder.

There are a number of Adobe AIR applications available now.

Would this also include AJAX applications like gmail? Certainly gmail
is popular.